ABC of oxygen: Oxygen transport---1. Basic principles

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ABC of oxygen Oxygen transport—1. Basic principles

Mammalian life and the bioenergetic processes that maintain cellular integrity depend on a continuous supply of oxygen to sustain aerobic metabolism. Reduced oxygen delivery and failure of cellular use of oxygen occur in various circumstances and if not recognised result in organ dysfunction and death. Prevention, early identification, and correction of tissue hypoxia are essential skills. An u...

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Delivery to organs and tissues The mechanisms controlling oxygen distribution are incompletely understood but involve a series of convective and diffusive processes. Convective oxygen transport refers to the bulk movement of oxygen in air or blood and depends on active, energy consuming processes generating flow in the tracheobronchial tree and circulation. Diffusive transport refers to the pas...

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The number of people travelling to the high altitude regions, especially South America, Nepal, and India, has risen enormously in the past 10 years. Without special climbing ability these trekkers can be exposed to altitudes they will not have encountered in their home countries. For example, the height of Everest base camp is 5500 m whereas the top of Mount Blanc, the highest mountain in the A...

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ژورنال

عنوان ژورنال: BMJ

سال: 1998

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.317.7168.1302